Today’s IRIA Outreach Programme was an academic feast.

Today’s IRIA Outreach Programme was an academic feast.

A special thanks to Rajendran sir for his vision and determination, Vijayan sir and Rajesh sir for their ever-present encouragement and to the organisers of the event from Calicut Medical College, ably led by Rahul and Noufal.

We honestly hope that there will be more such programmes in the future. Well done.

IRIA Kochi’s initiative for the Stem Cell Registry

IRIA Kochi’s initiative for the Stem Cell Registry to help those who are in need of Stem Cell Transplantation was held on 7th July at IMA House Kochi. 30 Radiologists and IMA members registered & gave buccal smear sample for this noble cause. Dr. Amel Antony, National IRIA Vice President inaugurated the registration by giving his buccal smear for HLA typing.
Dr. M. R. Balachandran Nair, President IRIA Kochi & Mr Deepu of DATRI spoke on the occasion.

 

PTLD

59 years old male, known case of post renal transplant was brought to the hospital with complaints of abdominal mass and discomfort.
Tru cut biopsy from omental deposit- IHC results confirm Non Hodgkin Lymphoma – Diffuse large B cell Lymphoma- non GCB type.
He received RCHOP on 08-05-19. He developed grade 4 neutropenia, NADR Total count was 100cells/ mm3.
Patient managed conservatively with Broad spectrum Antibiotics & GCSF.
Posttransplant lymphoproliferative disorders (PTLDs) are a group of diseases that range from benign polyclonal to malignant monoclonal lymphoid proliferations. They arise secondary to treatment with immunosuppressive drugs given to prevent transplant rejection. Three main pathologic subsets/stages of evolution are recognised: early, polymorphic, and monomorphic lesions. The pathogenesis of PTLDs seems to be multifactorial-EBV is main one .Antigenic stimulation Plasmacytoid dendritic cells (PDCs) , regulatory T cells are other factors .Whilst most are high-grade B-cell non-Hodgkin’s lymphoma (NHLs), a few are classical Hodgkin’s lymphomas. Rare cases have also been shown to be either of T-cell or NK-cell lineage
PTLD has a broad range of manifestations with extranodal involvement more common in the abdo- men than nodal involvement. In the abdomen, extranodal PTLD is seen as organ involvement, such as hepatic portal masses and bowel wall thickening.3 The anatomic distri- bution of PTLD is influenced by the allograft itself, pref- erentially in the anatomic region of the transplanted organ or within the allograft. The abdominal cavity is the body compartment most frequently involved by PTLD, and seen in 50–75% of patients with PTLD following renal, liver or heart transplantation.PET has emerged as an important diagnostic tool in the management of lymphoma with its superior sensitivity to anatomical imaging, particularly for extranodal disease